稳定和不稳定型心绞痛斑块CT特征的差异

Evaluation with Multislice Computed Tomography on Differences in Plaque Characteristics in Stable Angina Pectoris Versus Unstable Angina Pectoris

目的比较稳定型心绞痛(SAP)与不稳定型心绞痛(UAP)患者冠状动脉斑块CT特征的差异。方法搜集UAP和SAP各32例患者的MSCT图像进行对照分析。结果 UAP组和SAP组正性重构的发生率(26/45和7/54)差异有统计学意义(P<0.01)。点状钙化的发生率(10/17和9/33)差异有统计学意义(P<0.05)。偏心性斑块的发生率(39/45和32/54)差异有统计学意义(P<0.01)。软斑块的平均CT值[(34.0±13.7)HU和(68.7±29.4)HU]差异有统计学意义(P<0.01)。结论 UAP患者冠状动脉粥样斑块的主要CT特征包括正性血管重构、斑块密度低和点状钙化等。

Objective To compare plaque characteristics with muhislice computed tomography （MSCT） between pa- tients presenting with stable angina pectoris and unstable angina pectoris. Methods The MSCT images of 32 patients with UAP and SAP were compared respectively. Results The frequency of positive vascular remodeling was significantly differ- ent in UAP （ 26/45 ） and SAP （ 7/54 ） （ P 〈 0.01 ）. The frequency of spotty calcification was higher in UAP than that in SAP （10/17 and 9/33, P 〈 0.05）. The frequency of eccentric stenosis was significantly different in UAP（39/45） and SAP （32/54） （ P 〈 0.01 ）. The mean CT value of noncalcified plaques and calcified plaques was 34.0 ± 13.7 and 68.7 ± 29.4 HU respectively. Conclusion The main CT characteristics of plaques associated with UAP include positive vascular re- modeling, low plaque density, and spotty calcification.