冻融胚胎移植周期内膜准备方案的进展

Progress of Endometrial Preparation in the Frozen-thawed Embryo Transfer

冻融胚胎移植(frozen-thawed embryo transfer,FET)因其增加累计妊娠率,降低了体外受精周期的多胎妊娠风险及减少了中、重度卵巢过度刺激综合征(OHSS)的发生,比重复再次取卵周期耗时短等诸多优点而引起各生殖中心的重视。内膜准备方案是保证胚胎成功着床的关键,现有的内膜准备方式有自然周期、促排卵周期、激素替代周期等,探讨总结适合不同类型患者的最佳内膜准备方式对冻融胚胎有重要意义。

Frozen-thawed embryo transfer （FET） has gained more and more attention from many assisted reproductive centers due to that it increases the cumulative pregnancy rate, reduces the risk of multiple pregnancy in vitro fertilization cycle, reduces the incidence of moderate to severe ovarian hyperstimulation syndrome, and takes shorter that repeated oocyte retrieval. Endometrial preparation protocol is the key to successful implantation. Cur- rent endometrial preparation methods include nature cycle, ovarian stimulation cycle, hormone replace treatment cycle etc. It is important to study the optimal endometrial preparation protocol for different patients.