蛋白质组学技术在矽肺相关蛋白筛选中的应用

Application of proteomics technique in s creening of silicosis related proteins

矽肺的发生发展过程十分复杂,探讨矽肺发生过程中的关键蛋白质,对于矽肺发生机制的研究、矽肺的诊断和治疗有着重要意义。本文拟就蛋白质组学技术在矽肺相关蛋白筛选方面的应用以及存在的问题进行简要综述,以为同道提供工作参考。

The developing process of silicosis is very complex, so exploreing the key proteins involved in the process should be of great significance to the study on mechanism, diagnosis and treatment of silicosis. This article makes a brief review on the application of the proteomics technique in screening of silicosis related proteins on the basis of recent references, meanwhile, the problems existed in practice are also discussed in the paper.