期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

光动力治疗药物合成进展 被引量：2

Progress in the Synthesis of Photodynamic Therapy Drugs
下载PDF
导出
摘要 光动力疗法(Photodynamic Therapy,PDT)是利用光敏剂发生光动力反应进行疾病诊断和治疗的一种新技术。光敏剂经历了第一代光敏剂卟啉及其衍生物、第二代光敏剂酞菁类化合物以及第三代光敏剂,已经逐步走向成熟。本文主介绍了这三代光敏剂的性质及合成。 Photodynamic Therapy（PDT） was a new technology for disease diagnosis and treatment with photosensitizer conducting photodynamic reaction.Photosensitizer was gradually matured through the first-generation photosensitizers-porphyrin and its derivatives,second-generation photosensitizer-phthalocyanine compounds,as well as third-generation photo-sensitizer.The property and synthesis of the three generations of photosensitizers were described.
作者 杨琛
机构地区 中南大学化学化工学院
出处 《广州化工》 CAS 2012年第12期52-54,共3页 GuangZhou Chemical Industry
关键词 光动力疗法 光敏剂 合成过程 photodynamic therapy photosensitizers synthesis process.
分类号 O626.13 [理学—有机化学]
  • 相关文献

参考文献8

  • 1Emma S. Nyman, Paavo H. Hynninen. Research advances in the use of tetrapyrrolic photosensitizers for photodynamic therapy [ J ]. Journal of Photochemistry and Photobiology B : Biology,2004,73 : 1 - 28.
  • 2Christopher S. Foote. Type I and Type II Mechanisms of Photodynamic Action [ J]. ACS Symposium Series, 1987,339:22 - 38.
  • 3Ethan D. Sternberg, David Dolphin. Porphyrin - based photosensitizers for use in photodynamic therapy [ J ]. Tetrahedron, 1998,54 : 4152 - 4202.
  • 4U.S. Department of Health and Human Services, National Institute of Health, National Cancer Institute[ OL]. www. cancer, gov.
  • 5Karmakova, T. , A. Feofanov, et al. Distribution of metal - free sulfon- ated phthalocyanine in subcutaneously transplanted murine tumors[ J]. Journal of Photochemistry and Photobiology B - Biology, 2004,75 ( 1 - 2) :81 -87.
  • 6De Oliveira, C. A. , L. K. Kohn, et al. Photoinactivation of different human tumor cell lines and sheep red blood cells in vitro by liposome - bound Zn ( II ) Phthalocyanine : Effects of cholesterol [ J ]. Journal of Photochemistry and Photobiology B - Biology, 2010, 100 ( 2 ) :92 - 99.
  • 7Erdogmus, A. Nyokong, T. Synthesis of zinc phthalocyanine derivatives with improved photophysicochemical properties in aqueous media [ J ]. Journal of Molecular Structure,2010,977 ( 1 - 3 ) :26 - 38.
  • 8马金石.卟啉类第二代光敏剂的发展[J].感光科学与光化学,2002,20(2):131-148. 被引量：32

二级参考文献2

共引文献31

同被引文献69

  • 1张紫洞,熊方武.药物导致的变态反应、过敏反应及超敏反应[J].抗感染药学,2004,1(2):49-51. 被引量：60
  • 2黄齐茂,闻雪静,谢小英,胡磊,潘志权,徐汉生.新型金属卟啉光敏剂的合成及其抗肿瘤活性[J].武汉化工学院学报,2006,28(1):1-4. 被引量：5
  • 3周斯博,张智红,Onega V Ulianova,Sergey S Ulyanov,骆清铭.光动力作用对铜绿假单胞杆菌杀伤效应的研究[J].激光生物学报,2006,15(5):453-457. 被引量：6
  • 4Emma S, Nyman, Paavo H. Hynninen. Research advances in the use of tetrapyrmlic photosensitlzet for photodynamic therapy[J]. J Photochem Photobiol B, 2004, 73(1/2): 1-28.
  • 5Erdognms A, Nyokong, T. Synthesis of zinc phlhalocyanine detivalives with improved photophysicochemical properties in aclueousmedia[J].JMolSltuct, 2010, 977(1/2/3): 26-38.
  • 6Aekroyd R, Kelly C, Btvn N, et al. The histot of photodetection and photodynamic therapy [J]. Photochem Photobiol, 2001, 74(5): 656-669.
  • 7Overton G, Anderson GS, Belfote AD, et al. Reviews and forecasts for 2009-2010 global laser market[J]. Laser Focus WorldChin, 2010, 1(1): 8-14.
  • 8Smffilippo NJ, Hsi A, DeNittis AS, et al. Toxicity of photodynamle therapy after combined external beam radiotherapy and intraluminal braehytherapy for carcinoma of the upper aerodigestive tract[J]. Lasers Sm'g Me, 2001, 28(3): 278-281.
  • 9Xu R, Wang Q. Toward creation of a cancer drug toxicity knowledge base: automatically extracting cancer drug-side effect relationships fllll the litorature[J]. Am Med Infoml Assoc, 2013, 21(1) : 90-96.
  • 10Ochsner M. Photodynamic therapy: the clinical perspective. Review on applications for control of diverse timorous and non- tmnorous divetses[J]. Arzneinittel Fotschung, 1997, 47(11): 1185-1194.

引证文献2

二级引证文献9

广州化工
2012年 第12期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部