猪O型口蹄疫母源抗体消长规律的测定和免疫效果观察试验

Changes of Maternal Antibody Level of O-type Foot-and-mouth Disease and Test on Immunization Effect in Pig

本试验测定了6窝母猪免疫后产小猪0、1、7、14、21、28、35、42日龄O型口蹄疫母源抗体消长情况和首免、二免免疫抗体测定。结果表明:未吃初乳的0日龄仔猪均无母源抗体,1日龄仔猪母源抗体滴度达到高峰,以后逐渐降低;口蹄疫母源抗体对1～14日龄的仔猪有保护,部分仔猪在21日龄还有保护。28～35日龄首免后21日其免疫抗体合格率低于70%,28日后达到峰值86.7%,一个月后再免一次,则有效免疫抗体水平可维持较长时间,以后逐渐降低,至5个月后已不能保护,种猪此时须再次免疫接种猪口蹄疫疫苗。

The author detected O-type foot and mouth disease maternal antibody came from 0,1,7,14,21,28,35 and 42-day-age piglets born by 6 pigs.The immunity effect of first and second immunity also was observed.The results showed that maternal antibody didn’t existed in 0-day-age piglet without eating colostrums,and the highest level of it occurred in second day,then it gradually degraded.1～14-day-age piglets were protected by swine pest maternal antibody,some piglets also survived after 21-day-age.The piglets were first immunized in 28～35-day-age.The protected rate was lower than 70% in the 21st days and 86.7% after 8 days.The second immunity occurred in the 31st days after the first immunity.The immune antibody could sustain high level within 4 months after the second immunity,then the immunity protected rate gradually decreased,it couldn’t effectively protect the piglets after 5 months,so breeding pigs should be immunized again.