成年女性生殖道支原体感染治疗组与不治疗组的临床效果对比

Clinical comparison of treatment versus non-treatment in adult female patients with genital tract mycoplasma infection

目的探索女性生殖道支原体感染治疗与不治疗的临床效果,指导女性生殖道支原体感染的治疗时机。方法将500例女性生殖道支原体感染者分成治疗组(258例)与不治疗组(242例)。3个月后复查支原体,对前后两次检测结果进行统计学分析。结果治疗组258人治愈184例,不治疗组242例自愈130例,治疗组与不治疗组比较差异显著(P<0.01);治疗组中临床症状明显者与不治疗组中临床症状明显者比较,有效率有显著差异(P<0.01);治疗组中临床症状不明显者与不治疗组中临床症状不明显者比较,有效率无显著差异(P>0.05)。结论对女性生殖道支原体感染者是否进行治疗应视情况而定:临床症状明显者应进行治疗,但如果治疗仍不见好转的,不要再治疗;临床症状不明显者,不必进行治疗。

Objective To investigate the clinical outcomes of treatment versus non-treatment in adult female patients with genital tract mycoplasma infection and discuss the selection of the patients who should receive treatment.Methods Adult female patients with genital tract mycoplasma infection were divided into treatment group（n=258） and non-treatment group（n=242）.Mycoplasma spp.was reexamined in two groups of patients three months later,the results were analyzed.Results 184 of 258 patients in treatment group were cured;130 of 242 patients in non-treatment group were self-cured（P0.01）.There was significant difference in the number of patients with obvious clinical symptoms between treatment group and non-treatment group（P0.01）;however,no difference was found in the number of patients without obvious clinical symptom（P0.05）.Conclusion Whether or not to treat adult female patients infected with genital tract mycoplasma should depend on the clinical conditions of the patients： patients who have obvious clinical symptoms should be treated,but if their conditions are not improved,there is no need to try treatment again;while patients without obvious symptoms do not need to be treated.