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糖尿病膀胱病研究进展 被引量:9

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摘要 糖尿病膀胱病(diabetic cystopathy,DCP)是由Cai Frimodt-Moller在1976年提出的,又称糖尿病神经源性膀胱(diabetic neurogenic bladder,DNB),是糖尿病病人常见的泌尿系统慢性并发症,以排尿困难为主要症状,其发病率高,可达糖尿病患者的25%~85%[1]。DCP的发生不仅严重影响了患者的生活质量,长期患病还会引起上尿路功能损害,造成不可逆的肾功能损害。近年来随着糖尿病发生率的增高,DCP的病理生理及诊断、治疗成为了大家越来越关注的问题。
作者 王云汉 杨进
出处 《现代临床医学》 2012年第2期83-84,共2页 Journal of Modern Clinical Medicine
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参考文献19

  • 1Lee WC, Wu HP, Tai TY, et al. Effects of diabetes on female voiding behavior[J]. J Urol,2004,17(2) :989.
  • 2Chang S, Hypolite JA, Mohanan S, et al. A. Alteration of the PKC - mediated signaling pathway for smooth muscle contraction in obstruction -induced hypertrophy of the urinary bladder[ J ]. Lab Invest,2009,89 (7) : 823 - 832.
  • 3Kamata K, Inoue Kasuya Y. Changes incontractile responses of the urinary bladder to substance P in streptozotocin - induced diabetic rats [ J ]. Gen Pharmacol, 1993,24 ( 3 ) : 547 - 553.
  • 4Pak K J, Ostrom RS, Matsui M, et al. Impaired M3 and enhanced M2 muscarinic receptor contractile function in a streptozotocin model of mouse diabetic urinary bladder [ J ]. Naunyn Schmiedebergs Arch Pharmaeol,2010,381 (5) :441 -454.
  • 5Tammela TL, Briscoe JA, Levin RM, et al. Factors underlying the increased sensitivity to field stimulation of urinary bladder strips from streptozotocin - induced diabetic rats [ J ]. Br J Pharmacol, 1994, 113 (1) :195 -203.
  • 6Pak K J, Ostrom KS, Matsui M,et al. Ehlert,Impaired M3 and enhanced M2 muscarinic receptor contractile function in a streptozotocin model of mouse diabetic urinary bladder [ J ]. Naunyn Schmiedebergs Arch Pharmacol,2010,381 (5) :441 -454.
  • 7Yohannes E, Chang J, Christ GJ, et al. Proteomics analysis identifies molecular targets related to diabetes mellitus -associated bladder dysfunction [ J ]. Mol Cell Proteomics ,2008,7 (7) : 1270 - 1285.
  • 8Wang CC, Nagatomi J, Toosi KK, et al. Diabetes induced alternations in the biomechanical properties of the urinary bladder wall in rats [ J ]. Urology,2009,73 (4) : 911-915.
  • 9Zaruba RA, Epstein PN, Cart PA. Hyperglycemia alters enzyme activity and cell number in spinal sensory ganglia [ J ]. J Braclaial plex Peripher Never Inj, 2007, 2 : 11.
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二级参考文献5

  • 1BENNETT CJ,YOUNG MN,ADKINS RH,et al.Comparison of bladder management complication outcomes in female spinal cord injury patients[J].J Urol,1995,1458- 1460.
  • 2PEKKA HELLSTROM,PEKKA DORTELAINEN,MATTI KONTTURI.Late urodynamic finding after surgery for cauda equina syndrom cuased by a prolapsed lumbar intervertebral disc[J]. J Urol,1986,135:308.
  • 3BENNETT CJ,YOUNG MN,DARRINGTON H.Differences in urinary tract injury patients on intermittent catheterization[J].Paraplegia,1995,33(2):69- 72.
  • 4CARDENAS DD,HLOOTON TM.Urinary tract infection in persons with spinal injury[J].Arch Phys Med Rehabil,1995,76:272.
  • 5刘智.神经原性膀胱的评价和对策[J].现代康复,2000,4(6):803-804. 被引量:11

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