Duchenne型肌营养不良的诊治与管理,1:诊断和药物治疗
Diagnosis and Management of Duchenne Muscular Dystrophy,Part 1: Diagnosis and Pharmacological Management
摘要
Duchenne型肌营养不良（Duchenne muscular dystrophy，DMD）是一种常见的X连锁隐性遗传的致死性的肌肉变性疾病，发病率为1／3500活产男婴。一般3～5岁起病，7～13岁丧失独立行走能力，20～25岁死于呼吸道感染、心力衰竭或消耗性疾病。其发病是由位于X染色体上Xp21．2区域的dystrophin基因缺陷引起dystrophin蛋白的缺乏所致。
出处
《儿科药学杂志》
CAS
2012年第7期43-48,共6页
Journal of Pediatric Pharmacy
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