期刊文献+

采用不同时间给予替米沙坦治疗高血压病的疗效分析 被引量:1

下载PDF
导出
摘要 目的:探讨采用不同时间给予替米沙坦治疗对于高血压病患者血压的影响。方法:将2010年1月~2012年1月于我院治疗的150例原发性高血压患者平均随机成A、B两组,均采用血管紧张素II受体拮抗剂替米沙坦治疗,其中A组75例服药时间为早8点,B组75例服药时间为晚8点,两组的服用剂量均为1次80mg,1次/d。在治疗12周后评价两组患者临床治疗疗效。结果:A、B两组治疗方案的有效率分别为93.3%和94.7%,未见明显差异(P>0.05),且疗效显著。对比观察两组患者的白天、夜间、24小时的血压均值等血压情况发现,白天和24h的收缩压(SBP)和舒张压(DBP)均值两组患者数据相仿,不存在统计血差异(P>0.05);夜间SBP和DBP均值A组患者的血压水平明显高于B组,差异有统计学意义,P<0.05。结论:采用不同时间给予替米沙坦治疗对于高血压患者血压存在影响,晚间用药效果优于早上用药。
出处 《北方药学》 2012年第7期55-55,共1页 Journal of North Pharmacy
  • 相关文献

参考文献2

二级参考文献13

  • 1aChobanian AV, Bakris GL, Black HR, et al. Seventh, report of the joint national committee on prevention, detection, evaluation, and treatment of high blood pressure [ J]. Hypertension,2003 ;42 (6) : 1206-52.
  • 2Guideline Committee. 2003 european society of.hypertension-european society of cardiology guidelines for the management of arterial hypertension [ J]. J Hypertens ,2003 ;21 (6) : 1011-53.
  • 3Hermida RC, Calvo C, Ayala DE, et al. Administration time,dependent effects of valsartan on ambulatory blood pressure in elderly hypertensive subjects[ J]. Chronobiol Int,2005 ;22(4) :755-76.
  • 4Hermida RC. Ambulatory blood pressure monitoring in the prediction of cardiovascular events and effects of chronotherapy: rationale and design of the MAPEC study [ J ]. Chronobior Int,2007 (4) :749 -75.
  • 5Staessen JA ,Thijs L, Fagard R, et al. Predicting cardiovascular risk using conventional vs. ambulatory blood pressure in older patients with systolic hypertension [ J ]. JAMA, 1999 ;282 ( 6 ) : 539 -46.
  • 6Verdecchia P, Porcellati C, Sehillaci G ,et al. Ambulatory blood pressure : an independent predictor of prognosis in essential hypertension [J]. Hypertension, 1994 ;24 ( 6 ) :793-801.
  • 7Ohkubo T, Hozawa A, Yamaguchi J, et al. Prognostic significance of the nocturnal decline in blood pressure in individuals with and without high 24-h blood pressure :the ohasama study[ J]. J Hypertenh,2002 ;20(11 ) : 21830.
  • 8Dolan E, Stanton A, Thijs L, el.al. Supdriority of ambulatory over clinic blood pressure measurement in predicting mortality:the Dublin outcome study[ J]. Hypertension,2005 ;46 ( 1 ) :156-61.
  • 9Kikuya M, Ohkubo T, Asayama K, et al. Ambulatory blood pressure and 10-year risk of cardiovascular and noncardiovascular mortality. The Oh asama Study [ J ]. Hypertension,2005 ;45 ( 2 ) :240-5.
  • 10Hermida RC, Smolensky MH. Chronotherapy of hypertension [ J ]. Curr Opin Nephror Hypertens ,2004 ; 13 (5) :501-5.

共引文献15

同被引文献9

引证文献1

二级引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部