偏瘫患者脑脊液胱抑素C含量检测及分析

Detection and analysis of the patients with hemiplegia cerbrospinal fluid cystatin C content

目的:通过检测脑卒中不同程度偏瘫患者脑脊液胱抑素C含量改变,为临床提供诊断和治疗依据及预防干预措施。方法:以37例脑卒中偏瘫患者为研究对象,分为轻瘫、不完全性瘫和全瘫3组,测定其脑脊液中胱抑素C的含量,用微粒子增强比浊法与20例正常组对照进行分析。结果:脑卒中偏瘫患者脑脊液胱抑素C含量均低于对照组(P<0.01),且与病情呈反向关系,差异有统计学意义。结论:脑卒中偏瘫患者脑脊液胱抑素C的改变与脑部病况相关,含量值大小与病情轻重相关;治疗及预防干预对本病的康复有积极的作用。

Objective： By detecting cerebral breeders cystatin C levels in cerebrospinal fluid of patients with hemiplegia due to various changes,basis for clinical diagnosis and treatment and prevention interventions.Methods：In 37 patients with hemiplegia due to cerebral breeders for the study,and divided into paresis,group incomplete paraplegia and complete paralysis group,determination of cystatin C concentration in the cerebrospinal fluid,micro-particle enhanced turbidimetric method used with the normal set of comparative statistical analysis of 20 cases.Results：In cerebrospinal fluid in patients with hemiplegia after cerebral breeders cystatin C levels were lower than the control group（P0.01）,and inversely as the severity,significance of statistically significant differences.Conclusions：Cystatin C in cerebrospinal fluid in patients with cerebral hemiplegia due to sudden changes and conditions related to the brain,content size value and the relationship between illness severity scale,treatment and prevention intervention has a positive effect on the rehabilitation of the disease.