摘要
目的探讨他克莫司软膏联合氯雷他定治疗儿童特应性皮炎的临床疗效。方法选取2009年9月至2011年5月我院诊治的特应性皮炎患儿共160例,随机分为实验组和对照组,其中治疗组采用他克莫司软膏司联合氯雷他定治疗,对照组单纯口服氯雷他定。治疗后观察患者的皮肤状况,每周复诊1次,观察患儿的皮损及瘙痒情况。结果实验组与对照组的临床疗效总有效率差异具有统计学意义(97.50%VS 78.75%,P<0.05),实验组患儿的疗效总有效率明显较高;治疗结束2周后实验组患儿的临床体征与症状评分明显较低(P<0.05)。结论他克莫司软膏联合氯雷他定治疗儿童特应性皮炎,能够有效提高临床效果及改善临床体征与症状,值得在临床上推广应用。
Obiective Learn the effect of atopic dermatitis for children with tacrolimus and loratadine. Methods 160 children of atopic dermatitis from Sep 2009 to May 2011 divided into 2 groups. The experiment group uses tacrolimus and loratadine while the control group uses loratadine. Observe the skin state each week. Results The diverse of total effect rate of e group and c group has significance （97.50% VS 78.75%,P〈0.05）. The sign and symptom score of e group is lower （P〈0.05）. Conclusion Atopic dermatitis of children treated with tacrolimus and loratadine can increase effect and improve sign and symptom, worth using widely.
出处
《中国医药指南》
2012年第18期471-472,共2页
Guide of China Medicine
