237例早产相关因素的临床分析

Clinical Analysis on 237 Cases of Premature Labour

目的分析研究早产有关的危险因素及早产儿发病及死亡的相关因素。方法对2009年1月1日-2010年12月31日住院分娩237例早产患者的临床资料进行回顾性分析,并随机抽取足月分娩的237例进行相关对照。比较孕28～31+6、32～34+6、35～36+6周和足月孕龄新生儿窒息和新生儿死亡的差异。结果不明原因早产,胎膜早破,重度子痫前期,多胎妊娠,产前出血为早产原因的前5位;早产还与孕期母亲未做产前检查相关。早产与对照组新生儿窒息和死亡发生率差异有统计学意义(P<0.01)。结论早产病因复杂,减少早产的发生率关键是重视围产期保健,积极防治妊娠并发症。早产是围产儿发病和死亡的主要原因,重视早产的临床相关因素并采取相应措施,可降低围生儿并发症及死亡率。

Objective To analyze the dangerous factors associated with premature labor and the etiology of death in premature infants.Methods The clinical data of 237 patients with premature labour in our hospital from January 1,2009 to December 31,2010 were analyzed and compared to that of 237 randomly selected cases with full term deliver.Also,neonatal asphyxia and neonatal death rate of the control group and the cases of 28-31＋6 weeks gestation,32-34＋6 weeks gestation and 35-36＋6 weeks gestation were compared.Results The preceding causes of premature labour were spontaneous of premature labour for unexplained causes,premature rupture of membrane,pre-eclampsia,multiple pregnancy and pre-partum hemorrhage.It was related with premature labour that pregnant woman didn＇t accept prenatal examination.Significant difference was shown in the neonatal asphyxia and neonate death rate between the two groups（P0.01）.Conclusion The course of premature labour is complicated.The key issue to reduce the incidence of premature labour is to pay more attentions to the perinatal care,prevention of complications of pregnancy.Also,premature labour is the main causation of disease and death in infants.An intensive attention paid to the factors of premature labor and implementation of corresponding measures can decrease the complication and mortality in infants.