腹腔镜胃转流术治疗2型糖尿病合并高血压

The treatment effect of laparoscopic Roux-en-Y gastric bypass surgery in type 2 diabetes mellitus with hypertension

目的比较腹腔镜胃转流术与传统方法对2型糖尿病合并高血压患者的治疗疗效。方法将41例2型糖尿病合并高血压患者随机分为手术组和对照组,以糖化血红蛋白、血压、体重指数、血脂、左室质量指数、相对室壁厚度、左室射血分数为观察指标。结果与对照组比较,手术组糖化血红蛋白、血压、体重指数、血脂、E/A、左室质量指数上均有明显改善,其差异有统计学意义(P<0.05),对照组与手术组在左室射血分数上比较无统计学差异(P>0.05)。结论腹腔镜胃转流术治疗2型糖尿病合并高血压患者可明显改善糖化血红蛋白、血压、体重指数、血脂、E/A、左室质量指数。

Objective To compare the treatment effect of laparoscopie Roux-en-Y gastric bypass（LRYGB） and conventional treatment in type 2 diabetes mellitus （ T2DM ） with hypertension. Methods Totally 41 cases T2DM with hypertension were divided into 2 groups ： group A （23 patients received basal treatment for 6 months） , group B （ 18 patients received basal treatment, LRYGB surgery and followed- up for 6 months）. The baseline characters and parameters were detected. After treatment, changes from baseline of all parameters were re- corded. The differences between 2 groups were tested. Results compared with group A, distinctive decreases of blood pressure （ BP）, glycosylated hemoglobin A1 c （ HbA1 C ） , body mass index （ BMI）, lipid, left ventricular mass index （LVMI） were found in group B （ P 〈 0. 05 ） 6 months later, and E/A were increased in group B （P 〈 0.05 ）. Conclusion LRYGB surgery may has better improvement of HbAlc, BP, BMI, lipid, E/A, LVMI.