下肢深静脉血栓形成药物治疗150例疗效分析

Efficacy analysis of drug therapy in 150 cases with lower extremity deep venous thrombosis

目的探讨下肢深静脉血栓形成药物治疗的方法、疗效。方法回顾分析2005年5月至2010年7月对150例LDVT患者药物治疗资料,发病时间1 d～1个月,均为单肢发病,周围型60例,髂股型85例,混合型5例,全部病例经下肢血管彩超及静脉造影检查证实。治疗期间均未置放下腔静脉滤器,予抗凝、溶栓等治疗,时间10～14 d。结果 130例患者治疗期间患者水肿完全消退,2周后复查Doppler超声基本全程通畅;20例患者患肢轻度肿胀,Doppler超声复查存在髂股静脉短段闭塞,给予华法林维持治疗及弹力袜保护治疗6个月至1年。所有病例均获随访12～18个月,患肢肿胀明显消退,均无肺栓塞并发症。结论下肢深静脉血栓形成药物治疗安全、效果肯定。

Objective To explore the approach and efficacy of drug therapy in patients with lower extremity deep venous thrombosis. Methods Retrospectively analyze the data of drug therapy in 150 LDVT patients from May 2005 to July 2010 ,the period of onset was from 1 day to 1 month, all were single limb attacked, peripheral type in 60 cases, 85 cases of iliac and femoral type, mixed type in 5 cases. All cases by lower extremity vascular ultrasound were confirmed. Treatment time was 10 ~ 14 days without inferior vena cava filter. Results 130 patients eliminated edema completely during treatment, 2 weeks later, repeated Doppler ultrasound examination, blood stream was almost expedite; 20 cases with limb mild swelling, Doppler ultrasonic examination in iliac femoral venous short segment occlusion, were given the warfarin maintenance treatment and elastic stockings protection treatment for 6 months to 1 years. All cases were followed up for 12 to 18 months, limb edema eliminated significantly with no pulmonary embolism complications. Conclusion The medication for lower extremity deep vein thrombosis was safe and effectual.