绵阳市社区糖尿病视网膜病变的患病率调查及相关因素分析

Prevalence and correlative factors investigation of diabetic retinopathy in Mianyang

目的:探讨绵阳市糖尿病(DM)患者中糖尿病视网膜病变(diabetic retinopathy,DR)患病率和相关因素。方法:普查社区登记确诊的749例DM患者,通过询问和检查获得病史资料,采用眼底检查或眼底血管荧光造影确立DR诊断,并分别检测空腹血糖、糖化血红蛋白、血清脂联素。结果:DM患者749例中共确诊DR患者151例,DR的患病率为20.2%。非增殖型和增殖型DR分别为108例(71.5%)和43例(28.5%)。空腹血糖在DM、非增殖型糖尿病视网膜病变(NPDR)和增殖型糖尿病视网膜病变(PDR)患者中分别为7.86±0.93mmol/L,8.24±2.17mmol/L,8.35±3.89mmol/L,三者比较无明显差异(P>0.05)。糖化血红蛋白和血清脂联素在这三类居民中测得的结果分别为6.24%±1.34%,7.12%±1.51%,7.94%±1.75%和8.48±2.89mg/L,6.74±2.11mg/L,4.57±1.82mg/L,三者比较有明显差异。结论:在DM居民中DR患病率高,需密切监测DM患者的高糖化血红蛋白和低血清脂联素,以控制DR患病。

AIM： To investigate the prevalence and correlative factors of diabetic retinopathy （OR） in residents with diabetes mellitus（DM） in Mianyang. METHODS： Totally 749 cases with confirmed DM were enrolled. The data of disease history was collected by inquiry and examination. Examination of ocular fundus and/or fundus fluorescein angiography（FFA） were used to confirm the diagnosis of DR. Fasting sugar, glycosylated hemoglobin and serum level of adiponcetin were examined. RESULTS： Totally 151 （20.2%） residents were identified with DR. The incidence of single and proliferative DR was 71.5% （108 cases） and 28.5% （43 cases）, respectively. Fasting sugar was 7.86±0.93mmol/L, 8.24±2.17mmol/L, 8.35±3.89mmol/L in DM, single DR and proliferative DR residents, there were no statistical difference （ P〉 0.05）. Glycosylated hemoglobin and serum level of adiponectin were 6.24% ±1.34%, 7.12% ±1.51%, 7.94% ±1.75% and 8.48± 2.89mg/L, 6. 74 ± 2. 11mg/L, 4. 57 ± 1. 82mg/L respectively in residents with DM, single DR and proliferative DR, there were statistical difference of glycosylated hemoglobin and serum adiponectin level among three groups. CONCLUSION. The incidence of DR is high in residents with DM. High glycosylated hemoglobin and serum level of adiponcetin of DM patients should be closely monitored in order to control DR.