摘要
Ras基因是人类肿瘤中一种常见的癌基因,约有30%的恶性肿瘤存在Ras基因的点突变。皮肤肿瘤是一种常见的肿瘤,Ras基因及其信号转导通路的异常与皮肤肿瘤的发生、发展密切相关。文中就Ras基因及其信号转导通路与皮肤肿瘤关系作一综述。
Ras is a most common oncogene in human tumors, and its point mutations are found in 30% of human cancers. The abnormality of the Ras gene and its signal transduction pathway is found to be closely associated with the development and progression of skin cancer, a most common malignancy worldwide.
出处
《医学研究生学报》
CAS
北大核心
2012年第7期771-773,共3页
Journal of Medical Postgraduates
关键词
RAS基因
肿瘤
信号转导
Ras gene
Skin tumor
Signal transduction