孤立性肺结节空间分布特征及伴随恶性征象的影像学分析

Imaging analysis on spatial distribution characteristics and accompanying malignant features of solitary pulmonary nodule

目的探讨孤立性肺结节(SPN)的空间分布及其与伴随恶性征象间的关系。方法收集188例SPN患者,根据结节所处位置与支气管的关系,由肺门向胸膜将肺野分为内侧带、中间带及外侧带;然后再由肺尖向肺底,分为上野、中野及下野;最后再对所有结节伴随的恶性征象与分布区域进行统计分析。结果 188个SPN中,位于内侧带7个、中间带57个、外侧带124个,相应部位具有恶性征象结节的百分比分别为14.69%(1/7)、59.65%(34/57)、86.29%(107/124),总体差异有统计学意义(P<0.05)。病灶位于上野84个、中野18个、下野86个,相应部位具有恶性征象结节的百分比分别为84.14%(69/84)、55.56%(10/18)、73.26%(63/86),总体差异有统计学意义(P<0.05);组间两两比较,除肺上野与肺中野的结节数有差异外,其余组间差异无统计学意义。结论 SPN所具有的恶性征象与分布区域在横向空间具有差异性,在纵向空间不具有差异性。

Objective To explore the relationship between spatial distribution and accompanying malignant features of solitary pulmonary nodule（SPN）.MethodsA total of 188 patients with SPN were collected.According to the relationship of nodule location and bronchi,the pulmonary fields were divided into interior area,medial area and exterior area from hilus to pleura.Then pulmonary fields were classified as superior field,medial field and inferior field from apex to basis pulmonis.Distribution characteristics and accompanying malignant features of all lesions were statistically analyzed.ResultsThere were 7 SPN in interior area,57 in medial area and 124 in exterior area,and corresponding percentage of nodules with malignant accompanying features was 14.69%（1/7）,59.65%（34/57） and 86.29%（107/124）,respectively（P〈0.05）.The number of SPN in superior field,medial field and inferior field was 84,18 and 86,respectively.Corresponding percentage of nodules with malignant accompanying features was 84.14%（69/84）,55.56%（10/18） and 73.26%（63/86）,respectively（P〈0.05）,while in interblock comparison,no statistical difference was found except between superior field and medial field.ConclusionSpatial distribution characteristics and accompanying malignant features of SPN are significantly variable in horizontal space,but not in longitudinal space.