综合干预措施对类风湿关节炎患者生存质量的影响

Assessment of the Quality of Life in Patients with Rheumatoid Arthritis Receiving Characteristic Therapy of Traditional Chinese Medicine

目的:比较在非甾体消炎镇痛药和甲氨蝶呤基础上,应用中药内服、外敷兼康复训练对类风湿关节炎(RA)病人生存质量变化的影响,旨在科学评价RA治疗方案中综合干预措施的可行性和必要性。方法:80例病例来源于随机对照临床试验,以RA生活质量量表作为本研究测量的工具。结果:综合干预组治疗RA总有效率为91.7%,优于西药对照组(P<0.05);综合干预组治疗前后患者生理、心理、社会功能、健康自我认识分值较治疗前水平明显改善(P<0.01),优于西药对照组(P<0.05)。结论:综合干预措施治疗类风湿关节炎疗效佳,使RA患者有更高的生活质量。

Objective：To assess the quality of life （QoL） in rheumatoid arthritis （RA） patients with 3 -month character- istic therapy of traditional Chinese medicine （TCM） plus NSAIDs （nonsteroidal anti - inflammatory drugs） and metho- trexate （MTX） for reducing deformity and disability, comparing with NSAIDs and MTX alone. Method：The research design was a randomized controlled trial. The questionnaire for assessment of QoL in RA patients was established and published. Results：The total effective rate of TCM treatment group was 91.7%, which exceeded remarkably compared with the control group（P 〈0.05）; After treatment of the TCM characteristic therapy, the physical, social, emotional function, self- recognized health status of RA patients improved significantly（ P 〈 0.01 ）, and the effects exceeded com- pared with that of control group（P 〈0.05 ）. Conclusion：Characteristic therapy of traditional Chinese medicine is effec- tive for the patients with rheumatoid arthritis in the improvement of quality of life, and the effect is better than that of control group.