脑出血并脑微出血的临床与影像特征

Clinical and imaging Features of intracerebral hemorrhage with cerebral microbleeds

目的探讨脑出血并脑微出血的临床与影像特点。方法分析16例自发性脑出血并脑微出血患者的临床资料与MRI-SWI影像表现。结果患者平均年龄67.9岁。14例患者合并高血压病,9例为首次发病的脑出血患者,7例为再发脑出血患者。再发脑出血患者SWI检查全部发现脑微出血,其中6例(85.7%)微出血同时累及双侧半球多个脑叶及深部脑组织。首发脑出血组合再发脑出血组患者脑微出血的病灶数量均数分别为5.22±2.82和9.71±3.50,2组间微出血病灶数量存在统计学差异(P=0.013)。结论脑微出血与自发性脑出血关系密切,较多的脑微出血病灶可能预示着再发脑出血的风险增高。

Objective To study the clinical and imaging features of intracerebral hemorrhage with cerebral microbleeds. Methods 16 patients of spontaneous intracerebral hemorrhage with cerebral microbleeds were involved, and their clinical data were analyzed retrospectively. All patients were examined by MR susceptibility weighted imaging（SWI）. Results The average age of the patients was 67.9 years. 14 patients were complicated by hypertensive diseases. 9 patients were first onset of intracerebral hemorrhages, and 7 patients were recurrent intracerebral hemorrhages. All patients with recurrent intracerebral hemorrhages were detected cerebral microbleeds by SWI, and among them, 6 patients＇ cerebral microbleed scattered from lobes to deep brains. The average number of cerebral microbleeds in patients of first onset of intracerebral hemorrhages was 5.22 ±2.82, while in patients of recurrent intracerebral, the number was 9.71±3.50. Conclusion The relationship of cerebral microbleed and spontaneous intracerebral hemorrhage was close. Increasing numbers of cerebral microbleed may be a suggestive sign of recurrent intracerebral hemorrhage.