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载脂蛋白E遗传表型的分布及其与疾病的关系 被引量:2

The Distribution of Apoe Phenotypes and Its RelationshiP to Disease
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摘要 对35例正常人和152例患者的ApoE表型和等位基因频率分布进行了比较,并比较东西方民族间的异同。结果表明,东西方人群之间存在种族差异,健康人群未发现ApoE 2/2,E 2/2患者的RCT明显低于其它各遗传表型,而其TG明显高于其它各型。 The distribution of ApoE phenotypes and the frequency of ApoE alleles in 35 normal Chinese people and 152 patients were studied. The results were compared with those from Western populations. The study showed a real racial. difference between the two groups. No normal Chinese person was detected with an E 2/2 phenotype. In patients in whom E 2/2 phenotype was deteted, the RCT was markedly lower than in the rest of those who had ApoE phenotypes. The TG was markedly higher in patients who were E 2/2 than in the rest of ApoE phenotypes.
出处 《北京医学》 CAS 北大核心 1989年第3期149-151,共3页 Beijing Medical Journal
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同被引文献15

  • 1黄尚志,方炳良,初海鹰,袁丽芳,王玫,许顺斌,罗会元.苯丙氨酸羟化酶基因内短串联重复序列多态性的分析及应用[J].中华医学杂志,1995,75(1):22-24. 被引量:26
  • 2顾牛范,冯国鄞,江三多,钱伊萍,林嗣萃,吴晓东,任大明,江开达.中国汉族人群APOE等位基因频率的初步研究[J].中华医学遗传学杂志,1996,13(1):8-10. 被引量:26
  • 3张晓琴,肖劲松,黄朝云.载脂蛋白E基因多态性与血管性痴呆关系的研究[J].中华医学遗传学杂志,1997,14(1):31-34. 被引量:9
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