外周血和尿液红细胞平均体积差值在血尿定位诊断中的应用

Application of mCV of peripheral blood and urine red blood cell volume to iocalization diagnosis of hematuria

目的探讨外周血和尿液红细胞平均体积(MCV)差值在血尿的定位诊断中的临床意义,为临床血尿的诊断带来新思路。方法采用血细胞自动分析仪测定100例血尿患者的血MCV和尿MCV的值,计算两者之间的差值,分析其差值以及尿MCV与肾小球性源性血尿的相关性。结果发现肾小球源性血尿与非肾小球源性血尿患者的尿MCV比较,明显减少,P<0.05,差异有统计学意义;MCVU和MCV差值均与肾性血尿有高度相关性,r分别为0.709和0.792后者的相关性要高于前者。结论与血MCV相比,尿MCV以及血尿MCV的差值具有较高的敏感度和特异度,而血尿MCV的差值的特异性和敏感度更高,可以作为筛检血尿来源的较好的指标之一。

Objective Explore peripheral blood and urine average volume red blood cells （MCV） difference in the diagnosis of urine positioning clinical significance. Methods The blood cells were measured in 100 cases of patients with urine analyzer of blood and urine MCV. Calculation of the difference between the two, Analyzing the difference of urine MCV with glomerular haematuria relevance. Results Glomerular haematuria with MCVU and poor, respectively, in all have significant differences, P〈 0.05;the differences of MCV are highly correlated with renal hematuria, the R is 0.792 and 0.709, respectively, The correlation of the former is higher than the latter. Conclusion The differences of MCV has high sensitivity and specific degrees, It can be used as screening blood in the urine of good indicator for the source.