控制性降压在中耳胆脂瘤手术全身麻醉中的运用

Application of controlled hypotension used in general anesthesia of cholesteatoma surgery

目的:探析中耳胆脂瘤手术全身麻醉中控制性降压的临床方法和用药安全性。方法:对中耳胆脂瘤手术患者32例,随机分成两组,对照组16例使用硝酸甘油联合芬太尼,观察组16例使用丙泊酚联合瑞芬太尼,观察两组患者的血压、心率、血糖的变化情况和苏醒时间、手术时间以及术中出血量。结果:观察组在手术5点时间点的血糖、心率和血压稳定状况明显优于对照组(P<0.05)。观察组的出血量明显少于对照组(P<0.05),观察组的手术时间、苏醒时间短于对照组(P<0.05)。结论:丙泊酚联合瑞芬太尼在耳胆脂瘤手术全身麻醉中控制性降压疗效显著,临床建议进一步推广运用。

Objective Analysis of cholesteatoma surgery, general anesthesia -controlled hypotension in clinical methods and drug safe- ty. Method 32 patients of cholesteatoma surgery were randomly divided into two groups, control group of 16 patients using nitroglycerin combined with fentanyl,and observation 16 patients using remffentanil combined with profosol. Phenomenons were observed in patients with blood pressure,heart rate,blood glucose changes and recovery time,surgery time and blood loss. Results The 5 -point time in the surgery of blood glucose, heart rate and blood pressure stable condition better than the control group （P 〈 0. 05）. The observation group was signifi- cantly less than the control group of bleeding（P 〈 0. 05）. In the observation group, the operation time, recovery time shorter than the control group （P 〈 0. 05）. Conclusion The prepofol combined with remifentanil anesthesia in cholesteatoma surgery significantly effective in con- trolling blood pressure, which is worth further promoting.