5Noma K, Oyama N, Liao JK. Physiological role of ROCKs in the cardiovascular system[J]. Am J Physiol, Z006,290 (3) : C661-668.
6Laufs U, Kilter H, Konkol C, et al. Impact of HMG CoA reductase inhibition on small GTPases in the heart[J]. Cardiova Res,2002,53(4) ~911-920.
7Wang YX, da Cunha V, Martin-McNulty B, et al. Inhibition of Rho-kinase by fasudil attenuated angiotensin Ⅱ-induced cardiac hypertrophy in apolipoprotein E deficient mice[J]. Eur J Pharmacol, 2005,512(2-3) : 215-222.
8Yanazume T, Hasegawa K,Wada H et al. Rho/ROCK pathway contributes to the activation of extracellular signal-regulated kinase/GATA-4 during myocardial cell hypertrophy[J].J Biol Chem, 2002,277 (10) : 8618-8625.
9Maruyama Y, Nishida M, Sugimoto Y, et al. Ga12/13 mediates α1-adrenergic ieceptor induced cardiac hypertrophy[J]. Circ Res, 2002,91(10) :961-969.
10Soha M, Obata K, Ickihara S, et al. Attenuation of ventricular hypertrophy and fibrosis in rats by pitavastatin: potential role of the Rho A-exreacellular signal-regulated kinase serum response factor signaling pathway[J]. Clinical & Experi Pharmac Physiol, 2006,33 (12):1164-1171.
