血清超敏C反应蛋白测定在基层急性脑出血患者中的应用及意义

Changes of High sensitivity C-reactive Patients with unstable angina pectoris after Percutaneous Coronary Intervention and Their Connection with Prognosis

目的探讨基层急性脑出血患者血清超敏C反应蛋白(hs-CRP)测定意义。方法收集142例脑出血患者和健康对照者150名,用改良的爱丁堡斯堪的那维亚神经功能缺损评分量表(CSS)将脑出血患者分为轻型组43例、中型组61例、重型组38例。采用免疫透射比浊法测定他们的血清hs-CRP水平和CT检测脑出血体积。结果脑出血患者的血清hs-CRP浓度明显比对照组的高(U值=17.578,P<0.0001),在不同的时间点里,轻型组患者的血清hs-CRP浓度<中型组<重型组,并且第3天和第7天的血清hs-CRP浓度和脑出血体积明显相关。结论动态观察血清hs-CRP水平的变化能反映出急性脑出血患者的病情变化情况。

Objective To study the changes of serum levels of high sensitivity c-reactive （hs-CRP） in patients with acute cerebral hemorrhage. Methods 142 patients with cerebral hemorrhage were selected in the observation group,and 150 healthy individuals were enrolled in the control group,which were divided into mild group,moderate group and sever group by CSS in patients.The serum levels of hs-CRP was detected by immunoturbidimetry and the volume of cerebral hemorrhage was counted by CD. Results The serum levels of hs-CRP in patients in the observationgroup were higher than those in the control group（U =17.578,P〈0.0001）. For different types of cerebral hemorrhage,The serum levels of hs-CRP in patients with sever cerebra lhemorrhage were higher than moderate and mild cerebral hemorrhage in different observation days,and the serum levels of hs-CRP was significantly corre- lation with the volume of cerebral hemorrhage after the thith day and seventh day in patients.Conclution The changes of disease condition in patients with acute cerebral hemorrhage were dynamically observed by serum levels of hs-CRP