无创正压通气治疗急性心源性肺水肿临床疗效及安全性研究

The study of the clinical efficacy and safety of noninvasive positive pressure ventilation treatment to acute cardiogenic pulmonary edema

目的探究无创正压通气治疗急性心源性肺水肿临床疗效及安全性。方法将2010年6月~2011年10月在我院治疗的126例急性心源性肺水肿患者分为观察组和对照组,分别给予常规治疗和无创正压通气治疗,观察患者各指标变化情况,并进行疗效评定。结果 2组比较发现,观察组总有效率明显高于对照组;观察组在治疗2h后对PaO2及RF的改善比对照组显著（P〈0.05）;而2组间指搏SaO2差异无显著性（P〉0.05）。结论对急性心源性肺水肿患者采用无创正压通气治疗疗效显著,安全性高,价格低,操作简单,在临床实践中易于执行,是治疗急性心源性肺水肿的优先选择。

Objective To investigate the clinical efficacy and safety of noninvasive positive pressure ventilation treatment to acute cardiogenic pulmonary edema. Methods 126 cases with acute cardiogenic pulmonary edema treated in our hospital from June 2010 to October 2011 in our hospital were divided into observation group and control group, which were given conventional treat- ment and non-invasive positive pressure ventilation treatment, each index change was observed and efficacy was evaluated. Re- suits The total effective rate of the observation group was significantly higher than that; Of the observation group; in the therapeu- tic treatment group, after 2 h of the treatment, it has a better significant improvement in PaO2 and RF than that of the control group （P〈0.05）; SaO2 of the two groups was of no significant difference （P〉0.05）. Conclusion NPPV therapy is effective, safe, with low price and simple operation, which is easy to implement in clinical practice, and is the preferred choice for the treatment for patients with acute cardiogenic pulmonary edema patients.