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人胃腺癌组织中ANXA10意义及其与临床病理因素的关系的研究

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摘要 目的为胃腺癌的诊治、评估等寻找靶点。方法用免疫组织化学法,检测57对胃腺癌患者术后的癌组织及正常胃组织蜡块切片中ANXA10的表达。结果两组表达有显著差异(P=0.001)。在胃腺癌中它的表达与患者的性别、年龄、肿瘤直径、肿瘤位置无相关(P>0.05),与浸润深度、组织学分级、临床分期、有无区域淋巴结转移及远处转移有相关(P<0.05)。结论 ANXA10表达减少和失活是胃腺癌的重要特征之一,它的减少和失活可能促进胃腺癌的发生、发展;它的表达减少和失活可能是胃腺癌产生和其恶性程度高的重要原因之一。
机构地区 宜春市人民医院
出处 《中国卫生产业》 2012年第14期146-146,共1页 China Health Industry
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