逍遥散加味治疗抑郁症60例

Xiaoyao San Treatment of Depression 60 Cases

[目的]观察逍遥散加味治疗抑郁症的临床疗效和安全性。[方法]将60例符合条件的抑郁症患者随机分为治疗组和对照组,治疗组30例给予逍遥散加味治疗,对照组30例给予左洛复治疗,两组疗程均为8周,观察患者治疗前后的临床症状,做出疗效评价。[结果]逍遥散加味对抑郁症治疗有效率为83.00%与左洛复80.00%相当(P>0.05);逍遥散与左洛复治疗后HAMD_24分数明显低于治疗前(P<0.01),但两组间比较差异无统计学意义(P>0.05)。治疗组不良反应发生率为10.00%,对照组不良反应发生率为43%,治疗后逍遥散的TESS副反应量表分数明显低于左洛复(P<0.01)。[结论]逍遥散加味治疗抑郁症疗效与对照组相当,不良反应明显少于对照组。

[ Objective] Watch Xiaoyao San the clinical curative effect of treating depression and security. [ Methods ]60 patients with meet the conditions of the depression patients were randomly divided into the treatment group and control group, The treatment group 30 cases to give Xiaoyao San treatment, 30 patients in the control group to Zoloft treatment, Two groups of treatment for eight weeks, all the patients were observed before and after treatment of clinical symptoms and make curative effect evaluation. [ Results ] Xiaoyao San treat-ment for depression rate of 75.19% and Zoloft 73.6 （P 〉 0.05） ; Xiaoyao San and Zoloft treatment HAMD_24 scores significantly lower than before treatment（ P 〈 0.01 ） ;But the comparative differences between the two groups was statistically significant（ P 〉 0.05 ）. The treatment group was 16% , and adverse reactions in the control group was 46. 1% , and adverse reaction ; After treatment, the treatment of Xiaoyao San side effects scores significantly lower than Zoloft（ P 〈 0.01 ）. [ Conclusion ] Xiaoyao San curative effect and the treatment of depression in the control group, adverse reaction is obviously less than those in the control group.