消渴通脉胶囊对糖尿病周围神经病变患者ET、NO的影响

Xiaoke Tongmai Capsule on Diabetic Peripheral Neuropathy in Patients with ET,NO Clinical Study of the Effect

[目的]观察消渴通脉胶囊对糖尿病周围神经病变患者ET、NO的影响。[方法]60例患者随机分为对照组、治疗组各30例,两组均常规给予控制糖尿病的治疗,对照组在此基础上予维生素B1针及甲钴胺治疗;治疗组在对照组治疗基础上加用消渴通脉胶囊,治疗8周为1疗程。[结果]治疗组总有效率为90%;对照组总有效率为63%。加用消渴通脉胶囊可改善血黏度,有效降低血浆内皮素含量,增加一氧化氮含量,并可改善神经传导速度。[结论]消渴通脉胶囊治疗作用是多途径、多靶点、多环节的,为中医药防治糖尿病周围神经病变提供了一种科学实用的新思路和确实有效的新方法。

[ Objective] Xiaoke Tongmai capsule observed in diabetic patients with peripheral neuropathy ET, NO impact. [ Methods ] 60 cases were randomly divided into control group, 30 patients in each treatment group, two groups were given conventional treatment of diabetes control, the control group on the basis of the needle to the vitamin B1 and methylcobalamin treatment ; treatment group were treated based on the use of Xi- aoke Tongmai capsules for 8 weeks course of treatment. [ Results ] The total effective rate was 90% ; the con- trol group, the total effective rate was 63%. Xiaoke plus Tongmai capsule can improve blood viscosity, reduce plasma levels of endothelin, nitric oxide levels increase, and improve nerve conduction velocity. [ Conclusion ] Xiaoke treatment is Tongmai capsule multi -channel, multi -target, multi -link for the prevention and treat- ment of diabetic peripheral neuropathy medicine provides a scientific and practical new ideas and new methods really effective.