两种检测幽门螺杆菌感染方法对比分析

Comparison and analysis between two kinds of testing helicobacter pylori infection methods

目的对比分析13C-尿素呼气试验及快速尿素酶试验检测幽门螺杆菌的价值。方法对104例因出现上腹不适来本院行胃镜检查的患者分别行13C-尿素呼气试验(13C-UBT)和快速尿素酶试验(RUT)两种方法检测幽门螺杆菌(HP)并进行分析。结果 13C-UBT阳性80例,阳性率76.9%,RUT阳性78例,阳性率75%,二者均阳性76例,二者均阴性22例,两种方法检测幽门螺杆菌感染经用χ2检验方法比较P>0.05,其差异无统计学意义。结论 13C-UBT作为一种非侵入性的检测方法,具有简便、快速、无创伤,无放射性、可重复等优点,可作为HP诊断及评估HP治疗疗效的首选方法,适用于儿童、孕妇及年老体弱不适宜胃镜检查者,具有较好的临床实用价值。

Objective A comparative analysis of the 13 C breath test and urea--rapid urease test helicobacter pylori value. Methods 104 cases of epigastric discomfort to our hospital for being done gas- troscope inspection of the patients were performed respectively 13 C--urea expiratory test （13 C--UBT） and rapid urease test （RUT）, two methods detection helicobacter pylori （HP） were analyzed. Results 13 C--UBT positive in 80 cases, 76. 9% positive, RUT positive in 78 cases, 75% positive, both of these positives were 76 cases. Both of these negative were 22 cases. Two detection methods had helicohacter pylori infection by use of a chi-- square test method which wea more （P 〉 0.05）, the differ- ence was not statistically significant. Conclusions 13 C--UBT as a noninvasive test methods, which is simple, quick, no wound, no radiation, repeated, etc. It can be used as HP diagnosis and evaluation HP curative effect as a preferred way, It can be applied to children, pregnant women and old and frail, but not suitable for upper inspectors. It has good clinical practical value.