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坦索罗辛治疗输尿管中上段结石的前瞻随机对照研究 被引量:12

Tamsulosin in the treatment of patients with proximal and medial ureteral stones: prospective,randomized,comparative study
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摘要 目的探讨α1受体阻滞剂坦索罗辛对输尿管上、中段结石排石的影响。方法 142例患者入选本研究,结石大小4~10 mm,随机分为两组,观察组口服坦索罗辛+排石颗粒,对照组口服排石颗粒,疗程8周。比较两组患者的排石时间、排石率、止痛药的使用量及使用率、生活质量评分和药物副作用等。结果两组患者的排石时间、排石率、止痛药的使用量及使用率、生活质量评分、药物副作用的发生率均有差异性。结论α1受体阻滞剂坦索罗辛可以提高输尿管上、中段结石的排石率,缩短排石时间。 Objective To explore the efficacy of alpha α1-blocker for the stone expulsion of proximal and medial ureteral stones. Methods This study involved 142 patients. All patients, who had urereral stones with the diameter range from 4 to 10 mm, were randomly divided into two groups. The observation group received Tamsulosin with Paishi Keli, the control group received Paishi Keli for 8 weeks. The stone expulsion time, stone expulsion rate, analgesic dosages, usage rate of analgesic life, quality score and drug side-effect were compared between the two groups. Results A significant difference was observed in the stone expulsion time, stone expulsioe rate, analgesic dosages, usage rate of analgesic life, quality score and drug side-effect between the patients in two groups. Coneiusion Alpha α1-blocker tamsulosin proved to be safe and effective for the treatment of proximal and medial ureteral stones patients, as demonstrated by the increased stone expulsion rate, increased QOL and reduced expulsion time.
机构地区 解放军第 解放军第
出处 《临床军医杂志》 CAS 2012年第3期645-647,共3页 Clinical Journal of Medical Officers
关键词 Α1受体阻滞剂 输尿管结石 排石时间 排石率 alpha α1blocker ureteral stone stone expulsion time stone expulsion rate
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参考文献10

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二级参考文献41

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