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系统性和局限性硬皮病的诊断

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摘要 硬皮病或进行性系统性硬化症(SSc)是一种慢性的多系统结缔组织病,其病理生理特征是血管病变,胶原和细胞外基质成分的过度沉积造成的纤维变性和自身免疫的“三元体”,临床主要表现为雷诺现象,皮肤增厚和内脏器官受累(包括胃肠道、肺脏、心脏和肾脏)。此病分为局限性和弥漫性两类。
出处 《中国医刊》 CAS 2012年第7期16-19,共4页 Chinese Journal of Medicine
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