摘要
目的探讨真武汤对心肾阳虚型心力衰竭(CHF)患者血浆B型钠尿肽(BNP)与一氧化氮(NO)水平的影响。方法对照组选取60例CHF患者为研究对象,给予常规强心、利尿、扩血管等西医治疗;另选取132例在对照组的基础上加用真武汤加减治疗,设为观察组。比较两组患者的临床疗效、BNP及NO的变化。结果治疗4周后,观察组的总有效率为96.0%,显著高于对照组72.0%(P<0.05)。且观察组的BNP、NO水平改善显著优于对照组(P<0.05)。结论真武汤治疗CHF疗效确切,可明显改善患者的心功能。
Objective To evaluate the changes of serum BNP and NO in patients with chronic heart failure（Type of Heart-Kidney Yang Deficiency） treated with Zhenwu decoction.Methods 132 patients were divided into two groups.In control group,the 60 cases were given conventional cardiac,diuretic,vasodilator and other western medical treatment,and in experimental group,other cases were given modified Zhenwu decoction.The changes of serum BNP and NO and efficacy were compared between two groups.Results The effective rate was 96.0% and 72.0%（P〈0.05） in experimental and control group after four weeks treatment,the difference was significant.The serum BNP and NO declined significantly in experimental group（P〈0.05）.Conclusion Zhenwu decoction is effective in the treatment of chronic heart failure.
出处
《黑龙江医学》
2012年第6期407-408,419,共3页
Heilongjiang Medical Journal
