摘要
二新菲,命名 chrysotoxols A 和 B (1, 2 ) 并且 24 已知的混合物在“ Shihu ”的 2010 中国药典从就职种类的茎被孤立, Dendrobium chrysotoxum。所有结构被阐明由分光镜(NMR, MS,紫外并且红外) 有在文学的报导数据的方法和比较。化合物 2 和六已知的酚对二根人的肿瘤房间线(A549 和 HL-60 ) 为细胞毒素的活动被估计。结果显示 erianin 可以举办细胞毒素的活动,另外的六混合物在集中失去活动在下面到 105
Two new phenanthrenes, named chrysotoxols A and B (1, 2) and 24 known compounds were isolated from the stems of the accession species in 2010 Chinese Pharmacopoeia of"Shihu", Dendrobium chrysotoxum. All structures were elucidated by spectroscopic (NMR, MS, UV and IR) methods and the comparison with reported data in the literatures. Compound 2 and six known phenols were assessed for cytotoxic activity against two human tumor cell lines (A549 and HL-60). The results indicated that erianin may have cytotoxic activity and the other six compounds lost activity at the concentration down to 10^-5 mol·L^-1.