摘要
Two new phenanthrenes, named chrysotoxols A and B (1, 2) and 24 known compounds were isolated from the stems of the accession species in 2010 Chinese Pharmacopoeia of"Shihu", Dendrobium chrysotoxum. All structures were elucidated by spectroscopic (NMR, MS, UV and IR) methods and the comparison with reported data in the literatures. Compound 2 and six known phenols were assessed for cytotoxic activity against two human tumor cell lines (A549 and HL-60). The results indicated that erianin may have cytotoxic activity and the other six compounds lost activity at the concentration down to 10^-5 mol·L^-1.
Two new phenanthrenes, named chrysotoxols A and B (1, 2) and 24 known compounds were isolated from the stems of the accession species in 2010 Chinese Pharmacopoeia of"Shihu", Dendrobium chrysotoxum. All structures were elucidated by spectroscopic (NMR, MS, UV and IR) methods and the comparison with reported data in the literatures. Compound 2 and six known phenols were assessed for cytotoxic activity against two human tumor cell lines (A549 and HL-60). The results indicated that erianin may have cytotoxic activity and the other six compounds lost activity at the concentration down to 10^-5 mol·L^-1.