摘要
Two new tirucallane-type triterpenoids, 3a,24β＇,25-trihydroxy-21,21-dimethoxy-23-oxo-tirucall-7-ene （I） and 3a-acetoxy-21fl-methoxy-24,25,26,27-tetranortirucall-7-ene-23（21）-lactone （2）, were isolated from the stem barks ofAphanamixis grandifblia, and their structures were elucidated on the basis of spectroscopic data analysis includ- ing ID, 2D NMR, IR, and ESI-MS spectral methods. The two isolates were evaluated for their cytotoxicities using NCI-H460 and HeLa cell lines.
Two new tirucallane-type triterpenoids, 3a,24β＇,25-trihydroxy-21,21-dimethoxy-23-oxo-tirucall-7-ene （I） and 3a-acetoxy-21fl-methoxy-24,25,26,27-tetranortirucall-7-ene-23（21）-lactone （2）, were isolated from the stem barks ofAphanamixis grandifblia, and their structures were elucidated on the basis of spectroscopic data analysis includ- ing ID, 2D NMR, IR, and ESI-MS spectral methods. The two isolates were evaluated for their cytotoxicities using NCI-H460 and HeLa cell lines.
