术前使用立止血对减少TURP治疗前列腺增生症的效-价评估

Effect-cost Analysis of Preoperative Use of Reptilase in Patients Undergoing Transurethral Resection of Prostate

目的 :分析术前使用立止血对TURP治疗BPH的疗效 -成本比较。方法 :1998年5月～1999年6月行TURP治疗BPH病人63例 ,术前应用立止血肌注及静推各1KU ,与术后使用止血药对照组63例作止血效果及费用比较。结果 :术前使用立止血组病人术后发生出血及其他并发症均小于对照组 ,处理费用分别为 (620±22 56)元及 (1113±38 72)元 ,有显著差异。结论 :术前使用立止血能有效地预防术后出血及其他并发症发生 ,降低手术治疗费用。

OBJECTIVE:Using effect-cost analysis,to compare the preoperative use of reptilase in patients with benign prostate hyperplasis(BPH)who underwent transurethral resection of prostate(TURP)with controls METHODS:63 cases of BPH received i m and i v reptilase in dose of 1kilounit each administration route before undergoing TURP during the period May 1998-June 1999 The hemostatic effect and cost of treatment were compared with those of controls who received dicynone(a hemostatic agent)postoperatively RESULTS:The severity of postoperative bleeding as well as other complications in the reptilase group was less than that in the control group and the costs in the two groups were 620±22 56 and 1 113±38 72 yuan RMB respectively with significant difference between them CONCLUSION:Preoperative administration of reptilase in TURP can effectively prevent postoperative bleeding and other complications and can decrease the expenses of surgical treatment