噪声性听力损伤的治疗观察

Treatment of noise induced hearing damage

对具有不同程度听力损伤患者(共20例耳),在不脱产情况下,口服赛鲨力补氧胶囊25天(11.2g/d),观察治疗前后其听力和静脉血中的铜蓝蛋白酶、超氧化物歧化酶(SOD)活性及过氧化脂质(LPO)含量的变化。结果表明,口服赛鲨力补氧胶囊后,患者静脉血中的铜蓝蛋白酶、超氧化物歧化酶活性显著升高:语频段听力恢复的有效率为71.4％,高频有效率为78.9％。因此,鲨烯不仅可以改善体内的代谢物清除水平,而且能够显著改善职业性噪声导致的听力损伤。

Not being released from work, 20 cases of patients with different degrees of hearing damage orally take 96% squalene and 4% SOD capsule for.25 days (11.2 g/d) . Changes of subjects' hearing, of ceruloplasmin and SOD activity, and of LPO contents in venous blood are observed before and after treatment. The result shows that after taking 96 % squalene and 4% SOD, capsule ceruloplasmin and SOD activity rises obviously, effective rate of hearing recovery in speech frequency domain is 71.4% , and that of high frequency is 78.9% . Therefore, squalene can not only raise clearing level of internal metabolite, but also improve occupational noise induced hearing damage obviously.