原发性肝癌非手术治疗的临床疗效分析

Effects of Different Therapeutic Methods for Non-surgical Hepatocellular Carcinoma

探讨不同方法治疗原发性肝癌的临床效果。回顾分析144例接受非手术方法治疗的原发性肝癌患者临床资料;各组患者1、2、3年生存率为86.4%、68.3%、58.2%,85.2%、59.0%、42.1%,100%、100%、42.9%,100%、94.7%、63.2%;经Log-rank统计分析,肝动脉栓塞化疗与其他各治疗组生存时间有显著性差别(P<0.05);经COX回归分析显示影响预后的因素包括栓塞次数,临床分期和治疗方法(P<0.05)。栓塞次数,临床分期和治疗方法为影响生存率的独立危险因素,肝动脉栓塞化疗E治疗次数应适当。

To reveal the effects of different therapies for non--surgical hepatocellular carcinoma, the clinical datas of 144 patients were retrospectively analyzed. Survival rate of the patients in different group at 1,2,3 year was 86.4 %, 68.3 %, 58.2 % ; 85.2 %, 59.0 %, 42.1% ; 100 %, 100 %, 42.9 % ; 100 %, 94.7 %, 63.2 %. Log- rank analysis suggested there were significantly difference in TACE and other treatment groups. Cox%s proportional hazard regression model demonstrated that times of TACE,clinieal stage and treatment methods were the independent risk factors affecting the survival（P〈%0.05）. Times of TACE,clinieal stage and treatment methods can significantly affect the survival of non--surgical hepatocellular carcinoma patients.