氨磷汀在治疗特发性血小板减少性紫癜中的作用

The Role of Amifostine in Treating Idiopathic Thrombocytopenic Purpura

特发性血小板减少性紫癜(ITP)并不少见,该病诊断不难,治疗方法多。但本例患者高龄、既往治疗出现副作用,用药受限,常规药物效果不佳,经氨磷汀治疗而使患者得以痊愈,目前已随访观察5个月无复发。结合文献,氨磷汀对高龄、难治性病例安全有效,提示氨磷汀可能是ITP治疗中一种较有潜力的药物。

This is to discuss Amifostine mechanism by analyzing one case with Idiopathic Thrombocytopenic Purpura （ITP）. ITP is not difficult to diagnozed. Many drugs are used to treat it. One 92--year--old male patient with ITP was not ameliorated by routine treatment. Finally he was cured by Amifostine. Then he was followed--up for 5 months without recurrence. We can say that Amifostine is safe and effective, further more it is possible a potentional medicine to cure elderly serious ITP.