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干细胞疗法及其在脉络膜新生血管治疗中的应用前景

Stem cell therapy and its application to the treatment for choroidal neovascularization
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摘要 脉络膜新生血管形成(choroidal neovascularization,CNV)常造成严重视力损害,对其治疗方法的探索是相关医学工作者研究和关注的热点。研究发现干细胞参与CNV生成,为干细胞疗法治疗CNV带来契机。本文就干细胞疗法治疗CNV的原理、研究基础、治疗策略、初步探索、优势和前景等作一综述。 Choroidal neovascularization (CNV) is a common cause of severe and irreversible visual loss. Therefore, the exploration of the treatment for CNV is always the focus of relative medical researches. Investigations indicated that stem cells contribute to CNV formation, which brings opportunity for the applica-tion of stem cell therapy to CNV treatment. In this review, we discuss the principle, foundation, strategy, preliminary research, advantages and outlook of stem cells application.
出处 《国际眼科纵览》 2012年第3期177-182,共6页 International Review of Ophthalmology
关键词 干细胞疗法 脉络膜新生血管形成 stem cell therapy choroidal neovascularization
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  • 1Friedenstein A J, Petrakova KV, Kurolesova M, et al. Heterotopic of bone marrow. Analysis of precursor cells for oeteogenic andhematopoietic tissues. Transplantation, 1968, 6:230-247.
  • 2Pittenger MF, Mackay AM, Beck SC, et al. Multilineage potential of adult buman mesenchymal stem cells. Science, 1999, 284: 143-147.
  • 3Javazon EH, Colter DC, Schwarz EJ, et al. Rat Marrow stromal cells are more sensitive to plating density and expand more rapidly from single cell derived colonies than human nmrrow stromal cells. Stem Cells, 2001,19: 219-22.5.
  • 4Mori K, Gehlbach P, Ando A, et al. Regression of ocular neovascularization in response to increased expression of pigment epithelium-derived factor. Invest Ophthalmol Vis Sci, 2002, 43 : 2428 -2434.
  • 5Otani A, Kinder K, Ewalt K, et al. Bone marrow-derived stem ceils target retinal aslxocytes and can promote or inhibit retinal angiogenesis. Nat Med, 2002, 8:1004-1010.
  • 6Tomita M, Adachi Y, Yamada H, et 81. Bone marrow-derived stem cells can differentiate into retinal cells in injured rat retina. Stem Cells, 2002,20:279-283.
  • 7赵世红,何守志.氪激光诱导的大鼠脉络膜新生血管模型研究[J].中华眼科杂志,2003,39(5):298-302. 被引量:38

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