视神经鞘脑膜瘤的治疗进展

The treatment of optic nerve sheath meningioma

视神经鞘脑膜瘤是视神经鞘最常见的肿瘤。本文参考近10年来关于视神经鞘脑膜瘤治疗方面的文献，总结和分析视神经鞘脑膜瘤的治疗方法。认为采用合理的放射治疗方案可以有效提高或保持视力；手术切除易因视神经的机械性及缺血性双重损害而至患侧失明；对于视力无损伤或损伤轻微及视力损伤无进展的患者，可采取保守观察；目前尚未发现有效治疗视神经鞘脑膜瘤的药物。因此，对于需要采取临床治疗的视神经鞘脑膜瘤患者，可考虑采取三维适形立体定向放射治疗。

Optic nerve sheath meningioma is the most common tumor of the optic nerve sheath and its treatment methods are constantly progressing. This paper mainly discusses the progress of the treatment of optic nerve sheath meningiomas referring to the literatures in the past 10 years. The use of radiation treat-ment programs could effectively improve or maintain the vision; surgical resection could lead to the ipsilateral blindness beaeause of the mechanical and ischemic damage to the optic nerve ; a conservative observation was appropriate for the patients without vision injury, with minor injury, or with progression-free visual impair-ment; the effective drug had not yet found for the treatment of optic nerve sheath meningiomas. Therefore, the three-dimensional conformal stereotactie radiation therapy may consider adopting to those with optic nerve sheath meningiomas who need to be treated.