长春西汀联合红花注射液治疗脑梗死的临床观察

Clinical observation of Vinpocetine with honghua injection on the treatment of cerebral infarition

目的观察长春西汀联合红花注射液治疗脑梗死的临床疗效及安全性。方法选择急性脑梗死患者96例随机分为治疗组(50例)和对照组(46例),治疗采用综合疗法;治疗组加用长春西汀20mg+0.9%氯化钠注射液250ml静脉点滴1次/d,红花注射液20ml+0.9%氯化钠注射液250ml静脉点滴1次/d。对照组加用丹参注射液250ml静脉滴注,1次/d,两组均为14d一疗程。对患者进行治疗前、治疗后的脑神经功能缺损评分,同时测定治疗前后血脂、血流变学指标。结果疗程结束时,治疗组总有效率为92%,对照组总有效率为65.21%,两组比较有显著差异(P<0.01),且观察期间无明显不良反应。结论长春西汀联合红花注射液治疗脑梗死安全有效。

Objective To explore the clinical curative effect and safety of Vinpocetine with honghua intreating cerebral infarction. Methods 96 cases of patients with acute cerebral infarction were randomly di- vided into the treatment group （50 cases） and control group （n =46）, treated by comprehensive therapy. Treat- ment group and Vinpocetine 20 mg0. 9% 250 ml saline intravenously 1/d, honghua injection20 ml ＋ 0. 9% 250 ml saline intravenously 1 times,/＆ The control group plus danshen injection intravenous infusion with250 ml, 1/ d, two groups for 14 days in a course. Performed on patients before treatment, after treatment of cerebral neural function defect score, at the same time were measured before and after treatment of blood lipid, blood rheology. Results At the end of the treatment, the total effective rate in treatment group and 92% in control group, the total efficiency of 65.21%, two groups had significant difference （P 〈 0. 01 ）, and no obvious adverse reac- tions were observed during the. Conclusion Vinpocetine with honghua injection in treating cerebral infarction is safe and effective.