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急性白血病骨髓白血病细胞数下降的预后意义 被引量:3

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摘要 目的评价初发急性白血病化疗前后骨髓白血病细胞数下降的预后意义。方法回顾性分析29例初发急性白血病患者化疗前后骨髓白血病细胞数资料,比较持续缓解组(9例)、复发组(6例)、未缓解组(8例)和早期死亡组(6例)化疗前白血病细胞数、诱导化疗后的白血病细胞数和总生存时间的相关性。结果持续缓解组、复发组、未缓解组和早期死亡组化疗前的骨髓白血病细胞数分别为81.50%、84.75%、70.75%、93.00%,差异无统计学意义(P=0.196),化疗前骨髓白血病细胞数与总生存时间不相关(r=0.140,P=0.470);化疗后骨髓白血病细胞数分别为15.50%、7.75%、59.00%、56.00%,差异有统计学意义(P=0.045),化疗后骨髓白血病细胞数与总生存时间有相关性(r=-0.342,P=0.021)。结论急性白血病化疗前的骨髓白血病细胞数与预后无关,化疗后的骨髓白血病细胞数与患者的完全缓解率及长期生存有关。
作者 赵舒文
出处 《白血病.淋巴瘤》 CAS 2012年第6期371-372,共2页 Journal of Leukemia & Lymphoma
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参考文献4

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