烟雾病颈内外动脉造影和超微病理学研究——Ⅱ、烟雾病颈内外动脉造影和组织病理学观察

Anglographic and ultra-structral study of external and internal carotid artery in Moyamoya disease:Ⅱ.Cerebro-angiographic and pathohistologic observation of internal and external carotid arteries in Moyamoya disease

观察了13例病人的脑血管造影,发现烟雾病的动脉狭窄不仅发生在颈内 A 和椎-基底 A,也可发生在颈内 A 颈段和颈外 A 的颅内、外 A。血管造影观察与病理组织变化结合,发现颞浅 A 和脑膜中 A 常表现一段或一支狭窄,另一段或一支扩张,未见狭窄的节段也有内膜增生。说明烟雾病的病变广泛存在,颞浅 A、脑膜中 A 的血管造影改变应予重视。代偿扩张和侧枝 A 又发生狭窄,提示病变是反复发生的。

Cerebroangiogram of 13 patients with Moyamoyadisease were studied we found that the stenosis ofarteries not only in intracranial internal carotidarteries(ICA)and vertebor-basal arteries,but alsoin the cervical segments of ICA and the extra andintra-cranial branch of external carotid arteries.Com-bining with histopathologic changes we foundstenosis at one segment or one branch.and dilata-tion at another segment or branch of superficial tem-poral arteries(STA)and middle meningial arter-ies(MMA).In some segments although no stenosiswas observed by angiography.while there were in-timal porliferation.and thickening under histopatholo-gical observation.This study revealed that the pa-thologic changes of Moyamoya disease were existed at many arterial systems,the pathologic changesshowed it lasted for long times.