系统评价红花注射液治疗缺血性中风急性期的临床疗效研究

Clinical Cure Effect Study on Ischemic Stroke in Acute Period Treated with Red Flower Injection

[目的]系统评价红花注射液治疗缺血性中风急性期的临床疗效及安全性。[方法]运用系统评价方法,检索红花注射液治疗中风的随机对照试验,筛选合格研究,评价纳入研究质量,采用异质性检验、Meta-分析等方法统计相关数据。[结果]9项研究符合选择标准,采用随机效应模型统计,总有效率比较的相对危险度(RR)99%可信区间(99%CI)、需治疗病人数(NNT)(99%CI)、加权均数差(WMD)(99%CI)Meta-分析结果分别为1.19(1.10,1.28)、7.14(5.00,12.5)、-0.62(-1.10,-0.15)。[结论]红花注射液有益于改善出血性中风急性期患者的神经功能缺损状况,且安全性较好。

[ Objective ] To systemically evaluate the clinical effect and safety of Red Plower Injection treating acute ischemic stroke. [ Method ] Use systemic evaluation, retrieve the random control test of Red Plower Injection treating stroke, screen for qualified study, assess bring-into study quality, and take heterogeneity checkout and Meta-analysis for statistical data. [Result ] 9 items of study accord with standard; take random efficacy model statistics; compare total effective rates, RR 99% credible region （99%CI）, NNT （99%CI）, WMD （99%CI）, the Meta-analysis results are respectively 1.19 （ 1.10,1.28 ）, 7.14 （ 5.00,12.5 ） and -0.62 （ - 1.10, -0.15 ）. [ Conclusion ] Red Plower Injection is helpful to improving nerve function lack of acute ischemic stroke, with good safety.