摘要
[目的]探讨二甲双胍对伴高脂血症的不同葡萄糖代谢异常患者血脂影响的差异。[方法]52例2型糖尿病、40例糖耐量异常/空腹血糖过高(IGT/IFG)伴血脂异常的患者使用二甲双胍治疗12周,治疗前后测定患者血脂指标。[结果]二甲双胍可降低2型糖尿病和IGT/IFG患者的总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)(P<0.05),对高密度脂蛋白胆固醇(HDL-C)影响不明显。各组间治疗前后差异有统计学意义,且2型糖尿病组疗效更显著。[结论]二甲双胍可改善2型糖尿病和IGT/IFG患者的血脂代谢,且2型糖尿病组疗效更显著。
[ Objective ]To detect the different influence of melbine on lipid of different abnormal glucose metabolism accompanied with hyperlipemia. [Method] Observe 52 cases of type-2 diabetes and 40 cases of abnormal glucose tolerance/excess HBG（IGT/IFG） accompanied with abnormal lipid, treated with melbine for 12w, measure the lipid index before and after treatment. [Result] Melbine can reduce TC, TG and LDL-C, while it has no marked effect on HDL-C. There＇s difference of statistical meaning between before and after treatment, and esp. for type-2 diabetes group. [Conclusion] Melbine can improve lipid metabohsm of type-2 diabetes and IGT/IFG patients, esp. for type-2 diabetes.
出处
《浙江中医药大学学报》
CAS
2012年第6期691-692,共2页
Journal of Zhejiang Chinese Medical University
关键词
2型糖尿病
糖耐量异常
二甲双胍
血脂
type-2 diabetes
abnormal glucose tolerance
melbine
lipid
