皖北地区1～16岁儿童麻疹、风疹、流脑、乙脑抗体水平调查

Investigation of measles,rubella,epidemic cerebrospinal meningitis and Japanese encephalitis antibody levels among 1-16 years old children in Northern Anhui Province

目的了解皖北地区儿童麻疹病毒IgG、风疹病毒IgG、A群流行性脑脊髓膜炎IgG和流行性乙型脑炎病毒IgG 4种免疫抗体水平。方法采用整群抽样的方法,共采集1～16岁儿童手指血清样品5 542份,采用酶联免疫吸附试验法(enzyme-linked immunosorbent assay,ELISA)进行上述4种病毒IgG抗体水平监测。结果在调查的5 542份有效样本中,麻疹病毒、风疹病毒、A群流行性脑脊髓膜炎和流行性乙型脑炎病毒IgG抗体阳性率分别为95.9%、92.5%、89.4%和94.2%。结论皖北地区1～16岁儿童麻疹病毒IgG抗体、风疹病毒IgG抗体、A群流行性脑脊髓膜炎IgG抗体和流行性乙型脑炎病毒IgG抗体具有较高水平,形成了较牢固的免疫屏障,对控制上述4种传染病的暴发和流行起到了较好的作用。

Objective To investigate measles,rubella,epidemic cerebrospinal meningitis（ECM） and Japanese encephalitis（JE） immunoglobulin G（IgG） antibody levels among 1-16 years old Children in Northern Anhui Province.Methods A total of 5 542 blood samples of healthy children were collected quantitatively and measles,rubella,ECM and JE IgG antibody levels were detected by enzyme-linked immunosorbent assay（ELISA）.Results Among the subjects detected,the positive rates of measles,rubella,ECM and JE IgG antibodies was 95.9%,92.5%,89.4%,94.2% respectively.Conclusions Measles,rubella,ECM and JE IgG antibody levels of 1-16 years old children in Northern Anhui Province was relatively high,the firmer immune barrier to prevent children from measles virus（MV）,rubella virus（RV）,neisseria meningitis（NM） and Japanese encephalitis virus（JEV） was formed and obtained better effect on controlling the outbreak or epidemic of measles,rubella,ECM and JE.