抗矽口服液治疗矽肺患者的临床观察

Clinical observation of effect of anti-silicosis oral liquid

目的观察抗矽口服液辅助治疗矽肺患者的临床疗效。方法选择矽肺患者148例(Ⅰ期97例、Ⅱ期42例、Ⅲ期9例),随机分成治疗组和对照组2组,均常规给予抗炎、止咳、平喘治疗。治疗组在常规治疗的基础上,使用抗矽口服液10ml,2次/d,每周服药6 d,用药3个月,间隔1个月后重复给药3个月。对比临床症状和超氧化物歧化酶(SOD)活力。结果矽肺患者咳嗽、咳痰、胸痛、呼吸困难4项临床症状明显改善(P<0.05)。治疗后治疗组的SOD活力显著高于对照组,差异有统计学意义。结论采用中西药联合治疗矽肺的方法有利于提高药物疗效,减轻患者临床症状,值得推广使用。

[Objective]To observe the assistant effect of anti-sillicosis oral liquid on silicosis patients.[Methods]A total of 148 silicosis patients（SI 97cases,SII 42 cases,SIII 9 cases） were randomly divided into treatment group and control group,and received anti-inflammatory,？anti-cough and anti-asthma treatments.Based on the regular treatment,anti-silicosis oral liquid was given to treatment group 10ml twice a day,6 days for a week,3 months in total.Another treatment course was given after 1month.The clinical symptom and SOD activeness was compared at the end of medication.[Results]Cough,sputum,chest pain,dyspnea were obviously rereleased（P〈0.05）.The SOD activeness of treatment group was significantly higher than that of the control group after treatment.[Conclusion]The combination of western and Chinese medicine on treating silicosis takes more advantage on increasing drug efficacy and releasing symptom.It is worth spreading.