2011年沧州市手足口病流行病学分析

Epidemiological analysis of hand-foot-mouth disease in Cangzhou City in 2011

目的了解沧州市手足口病疫情流行特征,以预防控制手足口疫情发展及蔓延。方法对2011年疫情报告手足口病例流行病学资料和实验室核酸检测结果进行统计分析。结果 2011年沧州市手足口病病例累计报告14 855例,重症61例,死亡1例。比2010年同期(11 687例)上升27.11%。;对606例患者的咽试子等标本进行EV71、CoxA16和肠道通用病毒核酸检测,其中EV71型427份,CoxA16型89份,其他肠道病毒感染90份,分别占70.46%、14.69%和14.85%。结论沧州市2011年手足口病感染以EV71型病毒为主,与往年比较发病高峰期明显增高,年底拖尾现象比较严重,应加强各项防治措施,侧重EV71型病毒的防控。

[Objective]To understand the epidemiological characteristics of hand-foot-mouth disease in Cangzhou City,in order to control the development and spread of hand-foot-mouth disease.[Methods]The epidemiological data of hand-foot-mouth disease cases from epidemic reports and the results of nucleic acid detection in laboratory in 2011 were analyzed statistically.[Results]A total of 14 855 cases of hand-foot-mouth disease were reported in Cangzhou City in 2011,and there were 61 severe cases and 1 death case,which was increased by 27.11% compared to the same period last year.The nucleic acid detection for EV71,CoxA16 and other enterovirus was conducted in 606 throat swab samples.The results showed that 427 samples were positive for EV71,89 were positive for CoxA16,and 90 were other enterovirus infection,which accounted for 70.46%,14.69% and 14.85%,respectively.[Conclusion]The main pathogen of hand-foot-mouth disease in Cangzhou City in 2011 is EV71 virus,the peak has increased significantly as compared to the last year,and the tail phenomenon is obvious at the end of the year.It is necessary to strengthen the prevention and control measures,especially for EV71 virus.