2型糖尿病伴牙周炎患者牙周炎症程度与血糖水平分析

the effect of periodontal inflammatory on the level of Fasting blood glucose in type 2 diabetes patients with periodontitis

目的:分析2型糖尿病伴牙周炎患者牙周炎症程度对血糖水平的影响。方法:将213例2型糖尿病伴慢性牙周炎患者,根据根据牙周探诊深度(Probing depth,PD)和牙周附着丧失(Attach ment Loss,AL)的程度分为2组:2型糖尿病伴轻度慢性牙周炎组、2型糖尿病伴中重度慢性牙周炎组,分别测定血清h s-CRP、FPG水平并比较。结果:2型糖尿病伴中重度慢性牙周炎组较2型糖尿病伴轻度慢性牙周炎组血清FPG、hs-CRP水平升高,两组间FPG(t=7.144,P<0.001)、h s-CRP(t=13.493,P<0.001)差异具有统计学意义,而两组间年龄(t=-0.369,P=0.712)、性别(P=0.819)、饮酒(P=0.697)、吸烟(P=0.223)差异无统计学意义,偏相关分析发现PD与FPG(P<0.001)、h s-CRP(P<0.001)呈正相关。结论:牙周炎症可能会使2型糖尿病患者FPG、h s-CRP水平升高。

Objective： To analyze the effect of periodontal inflammatory on the level of fasting blood glucose in type 2 diabetes patients with periodontitis. Methods： According to the level of probing depth and attachment loss, 213 cases of type 2 diabetes patients with chronic periodontitis were divided into two groups： type 2 diabetes with slight chronic periodontitis group and type 2 diabetes with moderate to severe chronic periodontitis group. The level of hs-CRP, FPG were measured and compared. Results： The level of FPG （t = 7.144, P 〈 0.001）, hs-CRP （t = 13.493, P 〈 0.001） in type 2 diabetes with moderate to severe chronic periodontitis group were significantly higher than in type 2 diabetes with mild chronic periodontitis group. While there was no statistical difference of age （t = 0.369, P = 0.712）, gender （P = 0.819）, drinking alcohol （P - 0.697）, smoking （P = 0.223） between two groups. The result of correlation analysis shown that PD was positive correlation with the level of FPG and hs-CRP. Conclusion： Periodontal inflammatory may raise the level of FPG and hs-CRP in type 2 diabetes with chronic periodontitis patients.