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microRNA在间充质干细胞成骨分化中的调节作用 被引量：6

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摘要 间充质干细胞分化为成骨细胞的过程中受到基因表达的精确调控。近年来诸多研究表明microRNA(miRNA)在间充质干细胞的成骨分化过程中发挥着重要的调节作用。miRNA是一类小分子非编码RNA,主要通过与靶基因mRNA的碱基配对导致其降解或翻译阻遏,对基因进行转录后的调控。本文就不同miRNA分子对间充质干细胞成骨分化过程的双向调节功能及环境因素对其影响等方面做一综述。
作者 王俊成 刘洪臣
机构地区 解放军总医院口腔医学研究所
出处 《中华老年口腔医学杂志》 2012年第1期40-44,共5页 Chinese Journal of Geriatric Dentistry
基金 全军医学科技"十二五"重大项目(编号:AWS11J012-04)
关键词 间充质干细胞 MICRORNA 成骨分化
分类号 R329 [医药卫生—人体解剖和组织胚胎学]
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参考文献10

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二级参考文献21

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共引文献21

同被引文献138

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引证文献6

二级引证文献19

中华老年口腔医学杂志
2012年 第1期

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